Clinical Research
Our mission is grounded in evidence-based science. Below is a selection of peer-reviewed clinical research studies that demonstrate how vibration, neuromodulation, and dopamine regulation impact brain function, mood, and wellness.
Targeted Subcutaneous Vibration With Single-Neuron Electrophysiology
Vibrating specific parts of the body can change the activity of brain cells involved in mood and motivation, depending on where and how the vibration is applied.
Mechanical Stimulation Modulates Dopamine in the Nucleus Accumbens
Low-frequency vibration on the neck can increase dopamine and change brain cell activity in areas linked to motivation and addiction, using natural brain chemicals like opioids and acetylcholine.
The Effect of Beat Frequency Vibration on Sleep Latency and Neural Complexity: A Pilot Study
A specific vibration technique reduced time to fall asleep and enhanced brain activity associated with deeper, restorative sleep.
Mechanical Stimulation Alters Chronic Ethanol-Induced Changes to VTA GABA Neurons, NAc DA Release and Measures of Withdrawal
Mechanical stimulation helped counteract brain and behavioral effects of alcohol withdrawal in rats, suggesting improved mood and reduced relapse-related responses.
Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model
Whole-body vibration reduced brain and behavioral effects of opioid withdrawal in rats, showing promise as a supportive therapy for treating opioid addiction.
Amelioration of Anxiety Associated with Opioid Withdrawal by Activation of Spinal Mechanoreceptors Via Novel Heterodyned Whole Body Vibration
A specialized form of whole-body vibration significantly reduced anxiety in people undergoing opioid withdrawal, showing promise as a non-invasive, drug-free treatment option.
Voluntary Exercise Ameliorates Chronic Ethanol Withdrawal-Induced Adaptations of Opioid Receptor Expression in the Nucleus Accumbens, Dopamine Release, and Ethanol Consumption
Voluntary exercise reduced alcohol intake in mice and altered brain opioid receptor activity linked to addiction, highlighting its potential as a supportive therapy for alcohol-use disorder.